How to build this?

> Between each layer of seals use vacuum pumps to minimise any
> leakage to space. Vacuum pumps are capable of reducing the
> remaining leakage down to countable molecules if you really want
> that.

Do you think that this type of arrangement inserts a critical point
of failure if the vacuum pumps and their back-ups fail through some
type of localized catastrophe.

I'm thinking passive pressurization, rather than active
pressurization, presents a safer baseline.

If you were a ship designer, what benefits would you gain by
offering this type of active pressurization. I would think that
there would be a mass savings by avoiding the need to enclose the
centrefuges within a unitary pressure shell. What other benefits
would be worth making this trade-off?

TangoMan